Jurnalul de Chirurgie
 Jurnalul de chirurgie
Aparitie trimestriala in a doua luna a trimestrului
Published quarterly in the second month of the quarter
ISSN: 1584 - 9341 Vol.10 Nr.3 - Iulie-Septembrie 2014 | luni, 17 iunie 2019
ISSN: 1584 - 9341 Vol.10 No.3 - July-September 2014
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CLINICAL AND MORPHOLOGICAL CONSIDERATIONS IN CUTANEOUS MALIGNANT MELANOMA
Doinita Radulescu 1, Simona Stolnicu 2, S. Dumitriu 1

1 Department of Pathology, University of Medicine and Pharmacy „Gr.T.Popa”, Iasi
2 Department of Pathology, University of Medicine and Pharmacy, Tg. Mures
Jurnalul de chirurgie 2006; 2 (4):359-369
Full text: Format PDF (Romanian)

Abstract:

278 cases of cutaneous malignant melanoma admitted in „Emergency Clinic Hospital” Iasi between 1996-2006 have been described. Our cases showed that cutaneous malignant melanoma prevailed in females, has the highest incidence in the fourth decade, and is mostly located in lower limbs.

Malignant melanoma occured on healthy skin (205 cases), congenital nevus (9 cases), preexisting nevus (29 cases), lentigo maligna (14 cases), and as a subungual form (21 cases). Our cases have been classified as lentigo maligna, superficial spreading melanoma, nodular melanoma and as melanoma arising in a giant congenital nevus.

The retrospective comparison of our data reveals that in the evaluation of cutaneous malignant melanoma prognosis clinical parameters, as well as morphological ones, reprezented by Clark’s levels of invasion, Breslow’s thickness, tumour infiltrating lymphocytes, ulceration and vascular invasion, should be considered.

KEYWORDS: CUTANEOUS MALIGNANT MELANOMA, MORPHOLOGICAL PROGNOSTIC MARKERS

Correspondence: S. Dumitriu; e-mail:

 



: Creative Commons License
Jurnalul de chirurgie [Journal of Surgery] by Editorial Board, Department of Surgery University of Medicine and Pharmacy Iasi, E. Tarcoveanu, R. Moldovanu is licensed under a Creative Commons Attribution-NonCommercial-NoDerivs 3.0 Unported License.
Based on a work at www.jurnaluldechirurgie.ro.