Jurnalul de Chirurgie
 Jurnalul de chirurgie
Aparitie trimestriala in a doua luna a trimestrului
Published quarterly in the second month of the quarter
ISSN: 1584 - 9341 Vol.10 Nr.3 - Iulie-Septembrie 2014 | sâmbătă, 25 mai 2019
ISSN: 1584 - 9341 Vol.10 No.3 - July-September 2014
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TODAY’S POSSIBILITIES IN THE TREATMENT OF BILIARY OBSTRUCTION FROM PANCREATIC HEAD CANCER
A. Vasilescu, V. Strat
First Surgical Clinic „I. Tănăsescu-Vl. Buţureanu”
„Gr.T. Popa” University of Medicine and Pharmacy Iaşi
Jurnalul de chirurgie 2009; 5 (4): 326-334
Full text:
Format PDF (Română/Romanian)

Abstract:

In the last years significant progress has been made in the management of patients with pancreatic head cancer. The incidence of adenocarcinoma of the pancreas has been increasing world-wide in recent years, and it is currently the fourth leading cause of cancer-related mortality. Surgical resection offers a low success rate but provides the only chance of cure. Surgery ideally includes a radical (R0) resection and reestablishment of gastrointestinal continuity. A pancreatico-duodenectomy is usually surgical technique and only curative procedure. Contraindications for curative resection are the presence of distant metastases, peritoneal seeding and extension of tumour. Tumour infiltrations into mesenteric and portal vein are relative contraindications. The most important prognostic factors in radical resections has been shown to be surgically negative margins and nodal status. Systemic chemotherapy, radiation or a combination of chemotherapy and radiation have all been used either prior to resection (neoadjuvant therapy) or following surgical resection (adjuvant therapy) in an effort to improve the cure rate achieved with surgery alone.

KEY WORDS: PANCREATIC HEAD CANCER, PANCREATICO-DUODENECTOMY, PROGNOSTIC FACTORS, CHEMOTHERAPY, SURVIVAL

Correspondence to: Alin Vasilescu, MD; Assistant Professor, First Surgical Clinic „St. Spiridon” Hospital Iaşi, Independenţei Street, No 1, 700111, Iaşi, Romania; e-mail:



: Creative Commons License
Jurnalul de chirurgie [Journal of Surgery] by Editorial Board, Department of Surgery University of Medicine and Pharmacy Iasi, E. Tarcoveanu, R. Moldovanu is licensed under a Creative Commons Attribution-NonCommercial-NoDerivs 3.0 Unported License.
Based on a work at www.jurnaluldechirurgie.ro.