Jurnalul de Chirurgie
 Jurnalul de chirurgie
Aparitie trimestriala in a doua luna a trimestrului
Published quarterly in the second month of the quarter
ISSN: 1584 - 9341 Vol.10 Nr.3 - Iulie-Septembrie 2014 | vineri, 19 iulie 2019
ISSN: 1584 - 9341 Vol.10 No.3 - July-September 2014
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CARCINOID TUMORS OF JEJUNUM AND ILEUM. CLINICAL STUDY
O. Ciobotaru (1,2), Oana-Roxana Ciobotaru (2), Cr. Dragomir (3),
(1) PhD student, „Gr. T. Popa” University of Medicine and Pharmacy Iaşi
(2) Surgery Department, CFR Hospital Galaţi
(3) Third Surgical Clinic, „ Gr. T. Popa” University of Medicine and Pharmacy Iaşi
Jurnalul de chirurgie 2011; 7 (2): 166-172
Full text:
Format PDF (Română/Romanian)

Abstract:

Carcinoid tumors are the second most common tumor of small bowel (after adenocarcinoma) and are most commonly found in the ileum. Between 1998 and 2009,  there were studied 73 patients diagnosed with intestinal tumor in three hospitals in Iasi and Galati. Carcinoid tumors represents 15,38% of malignant tumors of jejunum and ileum. The average age of diagnosis was 60 years, 38% female and 62% male. 62,5% of patients came from urban areas and 37,5% in rural areas. Distal tumors (in the ileum) are more frequent than proximally located tumors (in the jejunum), incidence was 3:1. The main signs and symptoms were nonspecific: abdominal pain (100%), flatulence and nausea (75%). There were no correlations between admission and discharge diagnosis. The percentage of specimens positive for markers was as follows: Leu-7 87,5%, neuron-specific enolase (NSE) 75%, chromogranin A (CgA) 75%, serotonin 62,5%,  S100 protein 12,5%. Gastrointestinal radiology, ultrasound and CT were helpful in diagnosis, but none of them did not put the certain diagnosis in all cases that it has been made. At the moment of diagnosis half of patients had ganglion metastasis and 12,5% had metastasis, therefore only 12,5 percent survived after five years The results show us that preoperative diagnosis is often difficult to make, most of patients were diagnosed in advanced-stage. The five-year survival rate is slow. The most frequent tumor markers were Leu-7, neuron-specific enolase and chromogranin A.

KEY WORDS: CARCINOID TUMORS, SMALL BOWEL, IMMUNOHISTOCHEMISTRY

Correspondence to: Dr. Octavian Cătălin Ciobotaru, PhD student, „Gr. T. Popa” University of Medicine and Pharmacy Iaşi, Surgery Department, CFR Hospital Galaţi; email:



: Creative Commons License
Jurnalul de chirurgie [Journal of Surgery] by Editorial Board, Department of Surgery University of Medicine and Pharmacy Iasi, E. Tarcoveanu, R. Moldovanu is licensed under a Creative Commons Attribution-NonCommercial-NoDerivs 3.0 Unported License.
Based on a work at www.jurnaluldechirurgie.ro.