Jurnalul de Chirurgie
 Jurnalul de chirurgie
Aparitie trimestriala in a doua luna a trimestrului
Published quarterly in the second month of the quarter
ISSN: 1584 - 9341 Vol.10 Nr.3 - Iulie-Septembrie 2014 | sâmbătă, 23 martie 2019
ISSN: 1584 - 9341 Vol.10 No.3 - July-September 2014
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THERAPEUTIC APPROACHES IN ADVANCED BILIARY TRACT CANCER – EXPERIENCE OF FUNDENI DIGESTIVE ONCOLOGY DEPARTMENT
Adina Croitoru (1), Florina Pătraşcu (1), Iulia Gramaticu (2),
M. Andrei (3), Adriana Stoicescu (3), M. Diculescu (2)
(1) Department of Medical Oncology, Institute of Digestive Diseases and Liver Transplantation Fundeni (ICBDTHF)
(2) Clinic of Gastroenterology and Hepatology, ICBDTH Fundeni
(3) Clinic of Gastroenterology and Hepatology, SUUElias
Jurnalul de chirurgie 2011; 7 (2): 203-214
Full text:
Format PDF (Română/Romanian)

Abstract:

Cholangiocarcinoma is a rare malignancy, difficult to diagnose, associated with a high mortality. Diagnosis and treatment of these tumors are complex and require a multidisciplinary team. The prognosis is infaust, about 80% of patients being in unresectable stage at the moment of diagnosis. The incidence of intrahepatic cholangiocarcinoma is increasing worldwide, not very well explained, probably by improving diagnostic methods. A complete surgical resection with histologically negative resection margins is the only cure for cholangiocarcinoma, the results depending on technique used and the careful selection of patients. Chemotherapy, radiotherapy and biliary drainage are palliative methods of treatment. Liver transplantation for unresectable cholangiocarcinoma is currently contraindicated because of a high recurrence rate. Photodynamic treatment might improve quality of life. In the following, we will describe the results of a retrospective study which took place during the period 06.01.2004 – 01.01.2005, in the Department of Digestive Oncology - Fundeni Clinical Institute, including the patients with locally advanced and metastatic cholangiocarcinoma, treated by systemic chemotherapy. The results were compared with a similar study from our department during 2002-2003.

KEY WORDS: BILIARY TRACT CANCER, CHEMOTHERAPY, DESCRIPTIVE STUDY

Correspondence to: Prof. dr. Mircea Diculescu, Clinic of Gastroenterology and Hepatology, Institute of Digestive Diseases and Liver Transplantation Fundeni, Soseaua Fundeni 258, Sector 2 022328, Bucuresti, Romania



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Jurnalul de chirurgie [Journal of Surgery] by Editorial Board, Department of Surgery University of Medicine and Pharmacy Iasi, E. Tarcoveanu, R. Moldovanu is licensed under a Creative Commons Attribution-NonCommercial-NoDerivs 3.0 Unported License.
Based on a work at www.jurnaluldechirurgie.ro.