Jurnalul de Chirurgie
 Jurnalul de chirurgie
Aparitie trimestriala in a doua luna a trimestrului
Published quarterly in the second month of the quarter
ISSN: 1584 - 9341 Vol.10 Nr.3 - Iulie-Septembrie 2014 | marşi, 23 aprilie 2019
ISSN: 1584 - 9341 Vol.10 No.3 - July-September 2014
English
British Flag| Romana Romanian Flag
 
Creditare EMC
Colegiul Medicilor
Va invitam sa va inregistrati/abonati la Jurnalul de chirurgie pentru a beneficia de creditare EMC
User

Parola

Tine minte
Ti-ai uitat parola?
Syndicate

Advertisement

Elmed

Estima

Liamed

Listare E-mail

NUMARUL 2, VOL. 1, 2005

ARTICOLE ORIGINALE - ORIGINAL PAPERS

PARATHYROID CANCER. A REPORT OF THREE CASES
S. Lunca *, G. Bouras **
M.R. Diaconescu, M. Glod, I. Costea, Mirela Grigorovici, A. Covic*
Fourth Surgical Clinic,
Nefrology Clinic*
University of Medicine and Pharmacy Iasi
Jurnalul de chirurgie 2005; 1 (2):176-182
Full text: Format PDF (Romanian)

Abstract:

The parathyroid carcinoma (PTCa) is a rare and confusing condition mentioned in literature with incidence of 0,5-5% in the etiology of PT hyperfunction. Three cases representing 8,9% (!) from our experience in PT surgery are presented.

The first one was a 45 years old woman which at 40 months after resection of a right PT “adenoma” (15g) presents a clinical and biological recurrence of hyperparathyroidism (HP). At surgical re-exploration a new “tumour” (5g) was found on the same side and an “en block” resection including also the right side lobe of the thyroid was done. The paraffin sections identified a PTCa.

The second case was a young female (32 years) with a severe generalized bone disease and important hypercalcemia. A giant PT gland tumor of 35 g was easy and completely removed. The histological examination showed evidence of a PTCa she survived 14 months.

Finally the third patient was a 49 year old man with tertiary HP who is receiving maintenance hemodyalisis from 13 years. Ultrasonography revealed a thyroid nodule of 38 mm diameter of the left lobe. At operation only three PT glands was found and excised together with the “nodule”.

The definitive examination of the paraffin embedded material showed a PTCa. In all our three cases the surgery was the only beneficial therapy and two or three are still alive after four and one year respectively.

Patients with PTCA have clinically severe hyperparathyroidism related to the high calcium levels in the plasma and only the recognition and en bloc removal of the tumor at the time of the first operation assured best prognosis of this condition.

KEYWORDS: PARATHYROID CANCER, HYPERPARATHYROIDISM, HYPERCALCEMIA

Correspondence: Prof. Dr. M.R. Diaconescu , Clinica a IV-a Chirurgie, Spitalul Clinic C.F.R, Str. Garabet Ibraileanu nr.1, e-mail:



: Creative Commons License
Jurnalul de chirurgie [Journal of Surgery] by Editorial Board, Department of Surgery University of Medicine and Pharmacy Iasi, E. Tarcoveanu, R. Moldovanu is licensed under a Creative Commons Attribution-NonCommercial-NoDerivs 3.0 Unported License.
Based on a work at www.jurnaluldechirurgie.ro.