METASTATIC LYMPHADENOPATHY IN COLON CANCER V. Paunescu (1), D. Pop-Began (1), Valentina Pop-Began (1), M. Lisievici (2) (1) Clinica chirurgicala, Spitalul Clinic de Urgenta „Bagdasar-Arseni”, Universitatea de Medicina si Farmacie „Carol Davila” Bucuresti (2) Serviciul de Anatomie Patologica, Spitalul Clinic de Urgenta „Bagdasar-Arseni” Bucuresti Jurnalul de chirurgie (IaÅŸi). 2013; 9(1): 43-52. Full text: Format PDF (Română/Romanian) Abstract: INTRODUCTION: The incidence and prevalence of colon cancer is increasing in the last decades, in Romania. The aim of this paper is to evaluate the place of metastatic lymphadenopathy as risk factor for postoperative morbidity and mortality. MATHERIAL AND METHODS: We perfomed a prospective study; 126 patients with colon cancer were included and prospectively reviwed. RESULTS: The men / women ratio was 70 / 56. The mean age was 65.26 years old (range 20-89 years). Most cases were in stage III (n=72, 57.14%) and IV (n=49, 38.89%) with tumors located more frequently on the left colon (n=86, 68.25%) and especially on the sigmoid colon (n=64, 50.79%). 33.33% patients (n=42) were operated in emergency. Colic wall invasion depth (pT3=49, 38.9%, pT4=72, 57.1%) were accompanied by an increase in the number of affected regional lymph nodes (pN1=29, 23.0%, pN2=43, 34.1%). Postoperative complications occurred only in patients in stages III (n=11, 15.41%) and IV (n=15, 30.61%). The 30 days postoperative mortality rate was 19.04% (n=24), mostly in stage pT4 tumors (n=18, 25%). Metastatic adenopathy was found as risk factor for postoperative mortality rate: 16.66% (n=4) deaths for pN1, 30.23% (n=13) for pN2 and resoectively 13.07% (n=7) mortality rate for pN0. The five years survival rate was 100% for stage I, 59.64% for stage II, 33.57% for stage III and nul for stage IV. CONCLUSIONS: The presence of metastatic adenopathy is crucial in assessing the informational value of early and late postoperative evolution.
HOW TO CITE: Paunescu V, Pop-Began D, Pop-Began V, Lisievici M. [Metastatic lymphadenopathy in colon cancer] Jurnalul de chirurgie (Iasi). 2013; 9(1): 43-52. DOI: 10.7438/1584-9341-9-1-6.
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